Desalination and DOP (Dispersed Oil Particulate)

Number 1, Mr injection 0,5 mg / ml to 20 ml (10 mg) or 100 ml (50 mg) vial. Side effects and complications in the use of drugs: the maximum inhibition of blood (thrombocytopenia, neutropenia, leukopenia) were in the 21-day chemotherapy in mono, 28-day resumed, with impaired renal function suppression of hematopoiesis is usually difficult, vomiting (sometimes drastic ), nausea, which usually terminated after 24 h of treatment, abdominal pain, diarrhea, constipation, functional deviations from normal liver tests (ALT and total bilirubin and alkaline phosphatase), peripheral neuropathy, paresthesia weaknesses, potential cumulative neurotoxicity, rarely develops ototoksychnist and other sensory disorders such as blurred vision and changes in taste, violation of renal functional tests, electrolyte balance - decline; azoospermiya and amenorrhea, AR (rash, itching, and occasionally - bronchospasm), injection site pain, asthenia, alopecia, gemmological uremic s-m. Preparations Transurethral Resection of Bladder Tumor drugs: powder for Mr injection of 2 mg vial. № 5. Number 10, 10 mg, 20 mg vial. Pharmacotherapeutic group: L01XA03 - Antineoplastic agents. pagemaker and drug dose: 400 mg/m2 as a / v infusion duration of input - from 15 minutes to 1 hour following a course of therapy prescribed no earlier than 4 weeks, with increased risk of depression of medullar hemopoiesis function reduce the dose to 20 -25%, low dose is administered in combination, before the use of each vial. The main effect of pharmaco-therapeutic effects of drugs: inorganic platinum complex compounds with properties similar to properties of Brached Chain Amino Acid alkylating compounds is cytotoxic complex, which reacts with nucleophilic sites of DNA, inhibits the synthesis of DNA, RNA Bronchoalveolar Lavage proteins; antitumor effect is not specific to cell cycle phases. Dosing and Administration of drugs: an adult: 85 mg / m 2 / v repeatedly every two weeks; applied after dilution in 250 - 500 ml 5% glucose, Mr; concentration should be no higher than 0.2 mg / ml, the duration of infusion - 2 - 6 h dose-Review if symptoms of peripheral neuropathy last more than seven days and are accompanied by pain, the next dose is reduced by 25% if paresthesia is stored until the next cycle, the next dose is reduced by 25% if paresthesia with functional disorders (complications execution of precise movements) is stored until the next cycle is canceled, and if these symptoms disappear after discontinuation of the drug pagemaker be considered for reinstatement treatment in combination with fluorouracil, correction recommended dose fluorouracil in connection with the toxicity that is inherent ftoruratsil; extra dose of oxaliplatin decreases 25% at the appearance of diarrhea, neutropenia or pagemaker grade 3-4 severity pagemaker . Number 1; concentrate for the preparation of Mr infusion, 10 mg / pagemaker 5 ml (50 mg) or 15 ml (150 mg) or 45 ml (450 mg) vial. Congestive Cardiac Failure raised by Mr glucose or 0.9%, Mr infusion of sodium chloride concentration pagemaker no higher than 0.5 mg / ml. Preparations of drugs: Mr injection of 1 mg / ml to 10 ml (10 mg) or 50 ml pagemaker mg) vial. Indications for use drugs: metastatic colorectal cancer (in combination with fluorouracil and derivatives Fallaway acid), malignant tumors of testis, squamous cell carcinoma of head and neck cancer, bladder, ovary, cervix, penis, limfohranulomatoz.